Imported malaria in a tertiary hospital in Belgium: epidemiological and clinical analysis.
Identifieur interne : 000120 ( Main/Exploration ); précédent : 000119; suivant : 000121Imported malaria in a tertiary hospital in Belgium: epidemiological and clinical analysis.
Auteurs : J C Yombi [Belgique] ; S. Jonckheere ; G. Colin ; F. Van Gompel ; E. Bigare ; L. Belkhir ; B. VandercamSource :
- Acta clinica Belgica [ 1784-3286 ]
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Afrique, Antipaludiques (usage thérapeutique), Belgique (épidémiologie), Centres de soins tertiaires, Chimioprévention, Femelle, Humains, Loi du khi-deux, Mâle, Paludisme (), Paludisme (épidémiologie), Paludisme à Plasmodium falciparum (), Paludisme à Plasmodium falciparum (épidémiologie), Statistique non paramétrique, Sujet âgé, Voyage, Études rétrospectives.
- MESH :
- usage thérapeutique : Antipaludiques.
- épidémiologie : Belgique, Paludisme, Paludisme à Plasmodium falciparum.
- Adolescent, Adulte, Adulte d'âge moyen, Afrique, Centres de soins tertiaires, Chimioprévention, Femelle, Humains, Loi du khi-deux, Mâle, Paludisme, Paludisme à Plasmodium falciparum, Statistique non paramétrique, Sujet âgé, Voyage, Études rétrospectives.
- Wicri :
- geographic : Belgique.
English descriptors
- KwdEn :
- Adolescent, Adult, Africa, Aged, Antimalarials (therapeutic use), Belgium (epidemiology), Chemoprevention, Chi-Square Distribution, Female, Humans, Malaria (epidemiology), Malaria (prevention & control), Malaria, Falciparum (epidemiology), Malaria, Falciparum (prevention & control), Male, Middle Aged, Retrospective Studies, Statistics, Nonparametric, Tertiary Care Centers, Travel.
- MESH :
- chemical , therapeutic use : Antimalarials.
- geographic , epidemiology : Belgium.
- geographic : Africa.
- epidemiology : Malaria, Malaria, Falciparum.
- prevention & control : Malaria, Malaria, Falciparum.
- Adolescent, Adult, Aged, Chemoprevention, Chi-Square Distribution, Female, Humans, Male, Middle Aged, Retrospective Studies, Statistics, Nonparametric, Tertiary Care Centers, Travel.
Abstract
BACKGROUND AND OBJECTIVE
There has been a marked increase in tourism, immigration, and business travel to malaria-endemic areas. Non-immune individuals (western travellers) or immigrants living for more than one year in non-endemic areas who visit friends and relatives (VFR) are particularly susceptible to developing severe malaria when travelling to areas with high levels of transmission. In this study, epidemiological, clinical and biological features of malaria in travellers returning from endemic areas were analysed. This may help clinicians unfamiliar with malaria not to overlook this disease in its early stage, and to initiate prompt treatment.
PATIENTS AND METHODS
We retrospectively analysed all cases of patients who presented with malaria in our institution between 2003 and 2008.
RESULTS
Eighty patients were included. Most patients visited Africa (93.6%). Accordingly, P. falciparum was the main species identified (67/77 patients i.e. 87%). Sixty-five patients (65/78 i.e. 83.3%) had not taken any prophylaxis and 13 (16.7%) had taken it inadequately. Common clinical features were fever (80/80, 100%), influenza-like symptoms (16/80, 20.1%), respiratory symptoms (5/80, 6.3%), neurological symptoms (2/80, 2.5%) or digestive symptoms (15/80, 18.8%). Digestive symptoms were predominant in children < 16 y.o. (60% of these patients).
CONCLUSION
Imported malaria cases are mostly related to the lack of adequate use of chemoprophylaxis. Plasmodium falciparum is the main species responsible for imported cases of malaria in our institution. Clinical features vary, but fever is universally present at presentation. As such, all cases of fever upon return from a malaria-endemic area must be considered as malaria until proven otherwise, at least during the first three months after the return.
DOI: 10.2143/ACB.2964
PubMed: 23967717
Affiliations:
Links toward previous steps (curation, corpus...)
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Jonckheere</name></author><author><name sortKey="Colin, G" sort="Colin, G" uniqKey="Colin G" first="G" last="Colin">G. Colin</name></author><author><name sortKey="Van Gompel, F" sort="Van Gompel, F" uniqKey="Van Gompel F" first="F" last="Van Gompel">F. Van Gompel</name></author><author><name sortKey="Bigare, E" sort="Bigare, E" uniqKey="Bigare E" first="E" last="Bigare">E. Bigare</name></author><author><name sortKey="Belkhir, L" sort="Belkhir, L" uniqKey="Belkhir L" first="L" last="Belkhir">L. Belkhir</name></author><author><name sortKey="Vandercam, B" sort="Vandercam, B" uniqKey="Vandercam B" first="B" last="Vandercam">B. 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Non-immune individuals (western travellers) or immigrants living for more than one year in non-endemic areas who visit friends and relatives (VFR) are particularly susceptible to developing severe malaria when travelling to areas with high levels of transmission. In this study, epidemiological, clinical and biological features of malaria in travellers returning from endemic areas were analysed. This may help clinicians unfamiliar with malaria not to overlook this disease in its early stage, and to initiate prompt treatment.</p></div><div type="abstract" xml:lang="en"><p><b>PATIENTS AND METHODS</b></p><p>We retrospectively analysed all cases of patients who presented with malaria in our institution between 2003 and 2008.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Eighty patients were included. Most patients visited Africa (93.6%). Accordingly, P. falciparum was the main species identified (67/77 patients i.e. 87%). Sixty-five patients (65/78 i.e. 83.3%) had not taken any prophylaxis and 13 (16.7%) had taken it inadequately. Common clinical features were fever (80/80, 100%), influenza-like symptoms (16/80, 20.1%), respiratory symptoms (5/80, 6.3%), neurological symptoms (2/80, 2.5%) or digestive symptoms (15/80, 18.8%). Digestive symptoms were predominant in children < 16 y.o. (60% of these patients).</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Imported malaria cases are mostly related to the lack of adequate use of chemoprophylaxis. Plasmodium falciparum is the main species responsible for imported cases of malaria in our institution. Clinical features vary, but fever is universally present at presentation. As such, all cases of fever upon return from a malaria-endemic area must be considered as malaria until proven otherwise, at least during the first three months after the return.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23967717</PMID><DateCompleted><Year>2013</Year><Month>09</Month><Day>19</Day></DateCompleted><DateRevised><Year>2016</Year><Month>03</Month><Day>07</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1784-3286</ISSN><JournalIssue CitedMedium="Print"><Volume>68</Volume><Issue>2</Issue><PubDate><MedlineDate>2013 Mar-Apr</MedlineDate></PubDate></JournalIssue><Title>Acta clinica Belgica</Title><ISOAbbreviation>Acta Clin Belg</ISOAbbreviation></Journal><ArticleTitle>Imported malaria in a tertiary hospital in Belgium: epidemiological and clinical analysis.</ArticleTitle><Pagination><MedlinePgn>101-6</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND AND OBJECTIVE" NlmCategory="OBJECTIVE">There has been a marked increase in tourism, immigration, and business travel to malaria-endemic areas. Non-immune individuals (western travellers) or immigrants living for more than one year in non-endemic areas who visit friends and relatives (VFR) are particularly susceptible to developing severe malaria when travelling to areas with high levels of transmission. In this study, epidemiological, clinical and biological features of malaria in travellers returning from endemic areas were analysed. This may help clinicians unfamiliar with malaria not to overlook this disease in its early stage, and to initiate prompt treatment.</AbstractText><AbstractText Label="PATIENTS AND METHODS" NlmCategory="METHODS">We retrospectively analysed all cases of patients who presented with malaria in our institution between 2003 and 2008.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Eighty patients were included. Most patients visited Africa (93.6%). Accordingly, P. falciparum was the main species identified (67/77 patients i.e. 87%). Sixty-five patients (65/78 i.e. 83.3%) had not taken any prophylaxis and 13 (16.7%) had taken it inadequately. Common clinical features were fever (80/80, 100%), influenza-like symptoms (16/80, 20.1%), respiratory symptoms (5/80, 6.3%), neurological symptoms (2/80, 2.5%) or digestive symptoms (15/80, 18.8%). Digestive symptoms were predominant in children < 16 y.o. (60% of these patients).</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Imported malaria cases are mostly related to the lack of adequate use of chemoprophylaxis. Plasmodium falciparum is the main species responsible for imported cases of malaria in our institution. Clinical features vary, but fever is universally present at presentation. As such, all cases of fever upon return from a malaria-endemic area must be considered as malaria until proven otherwise, at least during the first three months after the return.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Yombi</LastName><ForeName>J C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>'Department of Internal Medicine, Infectious Diseases and Tropical Medicine Unit, Cliniques Universitaires St Luc, Université Catholique de Louvain, Brussels, Belgium. jean.yombi@uclouvain.be</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jonckheere</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Colin</LastName><ForeName>G</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Van Gompel</LastName><ForeName>F</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Bigare</LastName><ForeName>E</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Belkhir</LastName><ForeName>L</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Vandercam</LastName><ForeName>B</ForeName><Initials>B</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Acta Clin Belg</MedlineTA><NlmUniqueID>0370306</NlmUniqueID><ISSNLinking>1784-3286</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000962">Antimalarials</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000349" MajorTopicYN="N" Type="Geographic">Africa</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000962" MajorTopicYN="N">Antimalarials</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001530" MajorTopicYN="N" Type="Geographic">Belgium</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018890" MajorTopicYN="N">Chemoprevention</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016009" MajorTopicYN="N">Chi-Square Distribution</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008288" MajorTopicYN="N">Malaria</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016778" MajorTopicYN="N">Malaria, Falciparum</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018709" MajorTopicYN="N">Statistics, Nonparametric</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D062606" MajorTopicYN="N">Tertiary Care Centers</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014195" MajorTopicYN="Y">Travel</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>8</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>8</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2013</Year><Month>9</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23967717</ArticleId><ArticleId IdType="doi">10.2143/ACB.2964</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Belgique</li></country><region><li>Région de Bruxelles-Capitale</li></region><settlement><li>Bruxelles</li></settlement></list><tree><noCountry><name sortKey="Belkhir, L" sort="Belkhir, L" uniqKey="Belkhir L" first="L" last="Belkhir">L. Belkhir</name><name sortKey="Bigare, E" sort="Bigare, E" uniqKey="Bigare E" first="E" last="Bigare">E. Bigare</name><name sortKey="Colin, G" sort="Colin, G" uniqKey="Colin G" first="G" last="Colin">G. Colin</name><name sortKey="Jonckheere, S" sort="Jonckheere, S" uniqKey="Jonckheere S" first="S" last="Jonckheere">S. Jonckheere</name><name sortKey="Van Gompel, F" sort="Van Gompel, F" uniqKey="Van Gompel F" first="F" last="Van Gompel">F. Van Gompel</name><name sortKey="Vandercam, B" sort="Vandercam, B" uniqKey="Vandercam B" first="B" last="Vandercam">B. Vandercam</name></noCountry><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Yombi, J C" sort="Yombi, J C" uniqKey="Yombi J" first="J C" last="Yombi">J C Yombi</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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